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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
ARFG2_HUMAN
USC-OGP 2-DE database
:
ARFG2_HUMAN
ARFG2_HUMAN
General information about the entry
View entry in simple text format
Entry name
ARFG2_HUMAN
Primary accession number
Q8N6H7
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=ADP-ribosylation factor GTPase-activating protein 2; Short=ARF GAP 2; AltName: Full=GTPase-activating protein ZNF289; AltName: Full=Zinc finger protein 289;.
Gene name
Name=ARFGAP2
Synonyms=ZNF289
ORFNames=Nbla10535
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1242
:
pI=5.47; Mw=32128
Cross-references
UniProtKB/Swiss-Prot
Q8N6H7; ARFG2_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
ARFG2_HUMAN
Primary accession number
Q8N6H7
Secondary accession number(s)
B4DX29 B7Z9M7 D3DQQ9 Q3LIF2 Q8N3I1 Q96SX7
Sequence was last modified on
October 1, 2002 (version 1)
Annotations were last modified on
March 15, 2017 (version 128)
Name and origin of the protein
Description
RecName: Full=ADP-ribosylation factor GTPase-activating protein 2; Short=ARF GAP 2; AltName: Full=GTPase-activating protein ZNF289; AltName: Full=Zinc finger protein 289;
Gene name
Name=ARFGAP2
Synonyms=ZNF289
ORFNames=Nbla10535
Encoded on
Name=ARFGAP2; Synonyms=ZNF289; ORFNames=Nbla10535
Keywords
3D-structure
;
Acetylation
;
Alternative splicing
;
Coiled coil
;
Complete proteome
;
Cytoplasm
;
ER-Golgi transport
;
Golgi apparatus
;
GTPase activation
;
Membrane
;
Metal-binding
;
Phosphoprotein
;
Polymorphism
;
Protein transport
;
Reference proteome
;
Transport
;
Zinc
;
Zinc-finger
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AK027482; BAB55144.1
; -; mRNA
EMBL
AK301785; BAG63241.1
; -; mRNA
EMBL
AK315992; BAH14363.1
; -; mRNA
EMBL
AC090589; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
CH471064; EAW67963.1
; -; Genomic_DNA
EMBL
CH471064; EAW67968.1
; -; Genomic_DNA
EMBL
BC030148; AAH30148.1
; -; mRNA
EMBL
AL834337; CAD39004.1
; -; mRNA
EMBL
AB073358; BAE45716.1
; -; mRNA
CCDS
CCDS7926.1; -. [Q8N6H7-1]
; .
RefSeq
NP_001229761.1; NM_001242832.1
; .
RefSeq
NP_115765.2; NM_032389.4. [Q8N6H7-1]
; .
UniGene
Hs.436204; -
; .
PDB
2P57; X-ray
; 1.80 A; A=3-130
PDBsum
2P57; -
; .
ProteinModelPortal
Q8N6H7; -
; .
SMR
Q8N6H7; -
; .
BioGrid
124065; 17
; .
IntAct
Q8N6H7; 4
; .
STRING
9606.ENSP00000434442; -
; .
iPTMnet
Q8N6H7; -
; .
PhosphoSitePlus
Q8N6H7; -
; .
BioMuta
ARFGAP2; -
; .
DMDM
74729129; -
; .
EPD
Q8N6H7; -
; .
MaxQB
Q8N6H7; -
; .
PaxDb
Q8N6H7; -
; .
PeptideAtlas
Q8N6H7; -
; .
PRIDE
Q8N6H7; -
; .
DNASU
84364; -
; .
Ensembl
ENST00000524782; ENSP00000434442
; ENSG00000149182. [Q8N6H7-1]; .
GeneID
84364; -
; .
KEGG
hsa:84364; -
; .
UCSC
uc001ndt.4; human. [Q8N6H7-1]
; .
CTD
84364; -
; .
DisGeNET
84364; -
; .
GeneCards
ARFGAP2; -
; .
HGNC
HGNC:13504; ARFGAP2
; .
HPA
HPA016649; -
; .
HPA
HPA018152; -
; .
MIM
606908; gene
; .
neXtProt
NX_Q8N6H7; -
; .
OpenTargets
ENSG00000149182; -
; .
PharmGKB
PA162376868; -
; .
eggNOG
KOG0706; Eukaryota
; .
eggNOG
COG5347; LUCA
; .
GeneTree
ENSGT00390000005436; -
; .
HOGENOM
HOG000162970; -
; .
HOVERGEN
HBG050563; -
; .
InParanoid
Q8N6H7; -
; .
KO
K12493; -
; .
OMA
AKSPSWA; -
; .
OrthoDB
EOG091G0AS9; -
; .
PhylomeDB
Q8N6H7; -
; .
TreeFam
TF313985; -
; .
Reactome
R-HSA-6807878; COPI-mediated anterograde transport
; .
Reactome
R-HSA-6811434; COPI-dependent Golgi-to-ER retrograde traffic
; .
ChiTaRS
ARFGAP2; human
; .
EvolutionaryTrace
Q8N6H7; -
; .
GenomeRNAi
84364; -
; .
PRO
PR:Q8N6H7; -
; .
Proteomes
UP000005640; Chromosome 11
; .
Bgee
ENSG00000149182; -
; .
CleanEx
HS_ARFGAP2; -
; .
ExpressionAtlas
Q8N6H7; baseline and differential
; .
Genevisible
Q8N6H7; HS
; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0005794; C:Golgi apparatus
; IDA:HPA; .
GO
GO:0000139; C:Golgi membrane
; IEA:UniProtKB-SubCell; .
GO
GO:0005886; C:plasma membrane
; IDA:HPA; .
GO
GO:0005096; F:GTPase activator activity
; IEA:UniProtKB-KW; .
GO
GO:0046872; F:metal ion binding
; IEA:UniProtKB-KW; .
GO
GO:0006888; P:ER to Golgi vesicle-mediated transport
; TAS:Reactome; .
GO
GO:0015031; P:protein transport
; IEA:UniProtKB-KW; .
GO
GO:0006890; P:retrograde vesicle-mediated transport
; Golgi to ER; TAS:Reactome
InterPro
IPR001164; ArfGAP
; .
Pfam
PF01412; ArfGap
; 1; .
PRINTS
PR00405; REVINTRACTNG
; .
SMART
SM00105; ArfGap
; 1; .
PROSITE
PS50115; ARFGAP
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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